This essay traces the global journey of Neoplatonism across Europe, Africa and Asia and how it evolved through encounters with Christianity, Islam, and Hinduism. From its origins in Alexandria to its translation and reinterpretation in Ethiopia, the Islamic world and Mughal India, Neoplatonism was not simply transmitted, but was transformed. The essay reveals how a single philosophical system was reshaped across linguistic and cultural borders by those who engaged with it.